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A Buried Science Comes Back

A Chemist's Accident in 1943 Opened a Science That Was Then Buried

Promising Research Was Frozen by Fear and Politics, Not by Failed Results

A Science Moved Through Promise, Shutdown and Return

Mind, Room and Guide Shape the Experience

The Same Substance Can Become Awe or Terror, Depending on Mind, Room and Guide

Awe, Unity and a Loosened Sense of Self Mark a Mystical Experience

Preparation, the Session and Integration Work as One Container

A Quieter Self-Network Loosens Old Grooves

A Quieter Default Mode Network Loosens the Brain's Habitual Paths

Depression, Addiction and Obsession Share One Trap: a Mind Stuck in Its Groove

From a Quiet Hub to a Looser Mind: the Chain Researchers Propose

Early Signals Are Promising and Small

One Supported Session Eased End-of-Life Fear for Months in Small Trials

The Depth of the Experience Predicted Who Improved Most

Four Conditions, Four Early Signals, One Supported Process

Promising Is Not Proven

Five Weak Spots Separate a Promising Result From a Proven One

Hype Hides Behind Small Samples, Vivid Stories and Hopeful Language

Five Reasons a Promising Result Is Not Yet Proof

Changing Your Mind Without a Pill

Awe, Attention and Reflection Loosen Mental Ruts Without Any Drug

Insight Fades Unless It Is Practised Into a New Groove

A Weekly Practice Turns an Insight Into a New Groove

Check Your Understanding

Why Did Psychedelic Research Stall After 1970?

What Did the 2012 Imaging Study Find About the Default Mode Network?

Which Detail Most Limits the Early Trial Results?

Go Further

The Full Story Behind a Book About Psychedelics and the Mind

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A curious, careful guide to the science of psychedelics and the mind: how a promising field was buried and reopened, why mindset, room and guide shape the experience, what a quieter self-network does to old mental grooves, what early trials suggest about fear, depression and addiction, where hype outruns evidence, and how awe, attention and reflection can loosen a mental rut without any drug. .

How to Change Your Mind: what psychedelics reveal about the self

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